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Arthritis drug baricitinib meets major endpoint in Phase 3 RA-BEACON study Eli Lilly and Firm and Incyte Company today announce that the Phase 3 RA-BEACON study of the investigational medication baricitinib met its major endpoint of improved ACR20 response in comparison to placebo after 12 weeks of treatment. The study included patients with moderately-to-severely active rheumatoid arthritis who previously failed one or more tumor necrosis factor inhibitors and who were taking stable doses of typical disease-modifying anti-rheumatic drug therapy.