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AstraZeneca advancements MedImmune’s benralizumab to Stage III in severe asthma AstraZeneca today announced the beginning of the Stage III Windward program for benralizumab, a potential treatment for serious uncontrolled asthma produced by MedImmune, the business’s global biologics analysis and advancement arm. The purpose of CALIMA, the initial research in the Windward programme, would be to determine whether benralizumab decreases the amount of exacerbations in individuals with serious asthma that continues to be uncontrolled, despite receiving high dosages of inhaled corticosteroids in conjunction with a second controller like a long-performing beta agonist.