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These medicines may be necessary in some women that are pregnant with severe unhappiness in whom other approaches are inadequate. However, for many others, nondrug treatments, such as psychotherapy, can help, and aren't connected with complications like preterm birth. .. Antidepressant medications during pregnancy associated with increased prices of preterm birth Antidepressant medications taken by women that are pregnant are associated with increased rates of preterm birth. This finding reinforces the idea that antidepressants should not be used by pregnant women in the absence of a clear need that can’t be met through alternative approaches, say researchers from Brigham and Females's Medical center, Vanderbilt University, MetroWest INFIRMARY, and Tufts INFIRMARY.