Alteration in tumor suppressor gene TP53 has key role early in development of bone cancer The St. Jude Children's Research Hospital-Washington University Pediatric Tumor Genome Project found mutations in the tumor suppressor gene TP53 in 90 % of osteosarcomas, suggesting the alteration takes on a key role early in advancement of the bone cancers. The study was published today on the web ahead of printing in the journal Cell Reviews over the counter . The discovery that TP53 is changed in nearly every osteosarcoma also really helps to describe a long-standing up paradox in osteosarcoma treatment, which explains why at standard dosages radiation therapy is largely ineffective against the tumor.

Copyright 2009 Advisory Panel Kaiser and Company Family Foundation. All rights reserved.. Also in Global Wellness News: HIV/Helps in Uganda; medical apparatus in Tanzania; birth control in Afghanistan; Ethiopia malaria fight Adjustments Planned For Ugandan HIV/AIDS Advertising campaign The Uganda Helps Commission is revamping its national HIV information campaign after HIV prevention communications were less successful than hoped, PlusNews reports. Promotions aimed at ending cross-generational sex will become abandoned in favour of generic warnings about engaging in risky sex due to fears that teenagers may believe that sex within their own generation is risk-free. Officials also have said factors such as for example alcohol abuse, which predispose visitors to dangerous sexual behaviour, must be tackled alongside HIV avoidance .